ProtoPulse · CNAS therapeutic protocols
Data updated 19 Oct 2026, 22:37 · printed from ProtoPulse
Data updated 19 Oct 2026, 22:37 · printed from ProtoPulse
What's new – what changed with each order
New, amended and repealed protocols; medicines added and removed; changes of sublist and of prescription continuation by the family doctor (GP)
July 2026 · 32 changes (+9 medicines only mentioned in the text)
Protocol amended: 32
| Month | Type | Code | Protocol | Details | Level |
|---|---|---|---|---|---|
| July 2026 | Medicine added | L01XC12 | BRENTUXIMAB VEDOTIN | ETOPOSIDUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | L01XC18 | PEMBROLIZUMABUM | AXITINIBUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | L01XC24 | DARATUMUMABUM | MONTELUKASTUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | ALEMTUZUMABUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | EMTRICITABINUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | ETRAVIRINUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | NATALIZUMABUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | OFATUMUMABUM mentioned in the text | mentioned in the text |
| July 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | RITUXIMABUM mentioned in the text | mentioned in the text |
| July 2026 | Protocol amended | A021E | ACIDUM TIOCTICUM (ALFA-LIPOICUM) | ||
| July 2026 | Protocol amended | A10BK01 | DAPAGLIFLOZINUM | ||
| July 2026 | Protocol amended | A11DA03 | BENFOTIAMINUM | ||
| July 2026 | Protocol amended | A11DBN1 | COMBINATII | ||
| July 2026 | Protocol amended | A16AX08 | TEDUGLUTIDUM | ||
| July 2026 | Protocol amended | C02KX02 | TAFAMIDIS | ||
| July 2026 | Protocol amended | D11AH05-A | DUPILUMABUM | ||
| July 2026 | Protocol amended | D11AH05-BPOC | DUPILUMABUM | ||
| July 2026 | Protocol amended | J05AX28 | BULEVIRTIDUM | ||
| July 2026 | Protocol amended | L01EA06 | ASCIMINIBUM | ||
| July 2026 | Protocol amended | L01EL02 | ACALABRUTINIBUM | ||
| July 2026 | Protocol amended | L01EX22 | SELPERCATINIBUM | ||
| July 2026 | Protocol amended | L01XC-L04AJ | VASCULITE ANCA POZITIVE - DCI RITUXIMABUM**1 (original și biosimilar) și DCI AVACOPAN**1Ω | ||
| July 2026 | Protocol amended | L01XC12 | BRENTUXIMAB VEDOTIN | ||
| July 2026 | Protocol amended | L01XC17 | NIVOLUMABUM | ||
| July 2026 | Protocol amended | L01XC18 | PEMBROLIZUMABUM | ||
| July 2026 | Protocol amended | L01XC19 | BLINATUMOMABUM | ||
| July 2026 | Protocol amended | L01XC24 | DARATUMUMABUM | ||
| July 2026 | Protocol amended | L01XE50 | ABEMACICLIBUM | ||
| July 2026 | Protocol amended | L01XE54 | GILTERITINIB | ||
| July 2026 | Protocol amended | L02BB05 | APALUTAMIDUM | ||
| July 2026 | Protocol amended | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | ||
| July 2026 | Protocol amended | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | ||
| July 2026 | Protocol amended | L044L | PSORIAZIS CRONIC SEVER (ÎN PLĂCI) - AGENŢI BIOLOGICI ŞI TERAPII CU MOLECULE MICI CU ACŢIUNE INTRACELULARĂ | ||
| July 2026 | Protocol amended | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | ||
| July 2026 | Protocol amended | M05BX07 | VOSORITIDUM | ||
| July 2026 | Protocol amended | N007F | ARIPIPRAZOLUM | ||
| July 2026 | Protocol amended | N06AX26 | VORTIOXETINUM | ||
| July 2026 | Protocol amended | N07XX18 | VUTRISIRANUM | ||
| July 2026 | Protocol amended | R03AL09 | BECLOMETASONUM+FORMOTEROLUM+GLICOPIRONIU BROMIDUM | ||
| July 2026 | Protocol amended | R03AL11 | FORMOTEROLUM+GLICOPIRONIUM+BUDESONIDUM | ||
| July 2026 | Protocol amended | S01LA05 | AFLIBERCEPTUM |
April 2026 · 63 changes (+13 medicines only mentioned in the text)
New protocol: 35Protocol amended: 23Medicine added: 3Sublist changed: 2
| Month | Type | Code | Protocol | Details | Level |
|---|---|---|---|---|---|
| April 2026 | Medicine removed | L039M | ARTRITA IDIOPATICĂ JUVENILĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (original și biosimilar), ETANERCEPTUM**1 (original și biosimilar), ABATACEPTUM**1, TOCILIZUMABU… | TUBERCULINUM no longer mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | A16AX06 | MIGLUSTAT | BACLOFENUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | B02BX08 | AVATROMBOPAG | INTERFERONUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01EL03 | ZANUBRUTINIBUM | FLUDARABINUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01EL03 | ZANUBRUTINIBUM | RITUXIMABUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01XC38 | ISATUXIMABUM | CARFILZOMIBUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01XE23 | DABRAFENIBUM | TRAMETINIBUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01XE23-25 | DABRAFENIBUM + DCI TRAMETINIBUM | IBUPROFENUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L01XE23-25 | DABRAFENIBUM + DCI TRAMETINIBUM | PARACETAMOLUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | OZANIMODUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | RISANKIZUMABUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | L039M | ARTRITA IDIOPATICĂ JUVENILĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (original și biosimilar), ETANERCEPTUM**1 (original și biosimilar), ABATACEPTUM**1, TOCILIZUMABU… | CANAKINUMABUM | of the protocol |
| April 2026 | Medicine added | L039M | ARTRITA IDIOPATICĂ JUVENILĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (original și biosimilar), ETANERCEPTUM**1 (original și biosimilar), ABATACEPTUM**1, TOCILIZUMABU… | SECUKINUMABUM | of the protocol |
| April 2026 | Medicine added | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | BIMEKIZUMABUM | of the protocol |
| April 2026 | Medicine added | L044L | PSORIAZIS CRONIC SEVER (ÎN PLĂCI) - AGENŢI BIOLOGICI ŞI TERAPII CU MOLECULE MICI CU ACŢIUNE INTRACELULARĂ | DEUCRAVACITINIBUM mentioned in the text | mentioned in the text |
| April 2026 | Medicine added | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | TENOFOVIRUM ALAFENAMIDA mentioned in the text | mentioned in the text |
| April 2026 | Protocol amended | A014E | AGALSIDASUM BETA | ||
| April 2026 | Protocol amended | A16AB03 | AGALSIDASUM ALFA | ||
| April 2026 | Protocol amended | A16AX06 | MIGLUSTAT | ||
| April 2026 | Protocol amended | A16AX14 | MIGALASTATUM | ||
| April 2026 | Protocol amended | B02BX08 | AVATROMBOPAG | ||
| April 2026 | Protocol amended | C10AX13 | EVOLOCUMAB | ||
| April 2026 | Protocol amended | C10AX14 | ALIROCUMABUM | ||
| April 2026 | Protocol amended | CI01I-HTP | Protocol terapeutic în hipertensiunea arterială pulmonară: SILDENAFILUM, BOSENTANUM, AMBRISENTANUM, MACITENTANUM, RIOCIGUAT | ||
| April 2026 | Protocol amended | L01EL03 | ZANUBRUTINIBUM | ||
| April 2026 | Protocol amended | L01XC11-17 | NIVOLUMABUM + DCI IPILIMUMABUM | ||
| April 2026 | Protocol amended | L01XC38 | ISATUXIMABUM | ||
| April 2026 | Protocol amended | L01XE23 | DABRAFENIBUM | ||
| April 2026 | Protocol amended | L01XE23-25 | DABRAFENIBUM + DCI TRAMETINIBUM | ||
| April 2026 | Protocol amended | L01XE26 | CABOZANTINIBUM | ||
| April 2026 | Protocol amended | L01XX71 | TISAGENLECLEUCEL | ||
| April 2026 | Protocol amended | L02BX04 | RELUGOLIXUM | ||
| April 2026 | Protocol amended | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | ||
| April 2026 | Protocol amended | L039M | ARTRITA IDIOPATICĂ JUVENILĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (original și biosimilar), ETANERCEPTUM**1 (original și biosimilar), ABATACEPTUM**1, TOCILIZUMABU… | ||
| April 2026 | Protocol amended | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | ||
| April 2026 | Protocol amended | L044L | PSORIAZIS CRONIC SEVER (ÎN PLĂCI) - AGENŢI BIOLOGICI ŞI TERAPII CU MOLECULE MICI CU ACŢIUNE INTRACELULARĂ | ||
| April 2026 | Protocol amended | LB01B | HEPATITĂ CRONICĂ ŞI CIROZĂ HEPATICĂ CU VIRUS VHB | ||
| April 2026 | Protocol amended | M05BX07 | VOSORITIDUM | ||
| April 2026 | Protocol amended | N03AX26 | FENFLURAMINUM | ||
| April 2026 | New protocol | A03AB02 | GLICOPIRONIUM BROMIDUM | GLICOPIRONIU BROMIDUM, GLICOPIRONIUM BROMIDUM | |
| April 2026 | New protocol | A05AX04 | MARALIXIBATUM | MARALIXIBATUM | |
| April 2026 | New protocol | A05AX05 | ODEVIXIBATUM | ODEVIXIBATUM | |
| April 2026 | New protocol | A07EA06 | BUDESONIDUM | BUDESONIDUM | |
| April 2026 | New protocol | A16AB13 | ASFOTAZA ALFA | ASFOTAZA | |
| April 2026 | New protocol | A16AB14 | SEBELIPASE ALFA | SEBELIPASE ALFA | |
| April 2026 | New protocol | A16AB20 | PEGUNIGALSIDASUM ALFA | PEGUNIGALSIDASUM ALFA | |
| April 2026 | New protocol | A16AX04 | NITISINONUM | NITISINONUM | |
| April 2026 | New protocol | C10AX06 | ICOSAPENT ETHYL | ICOSAPENT ETHYL | |
| April 2026 | New protocol | C10AX18 | VOLANESORSENUM | VOLANESORSENUM | |
| April 2026 | New protocol | H02CA02 | OSILODROSTATUM | OSILODROSTATUM | |
| April 2026 | New protocol | L01EC03-FE01 | ENCORAFENIBUM+ CETUXIMABUM | CETUXIMABUM, ENCORAFENIBUM | |
| April 2026 | New protocol | L01EE02-EC01 | COBIMETINIBUM + VEMURAFENIBUM | COBIMETINIBUM, VEMURAFENIBUM | |
| April 2026 | New protocol | L01EE03-EC03 | BINIMETINIBUM + ENCORAFENIBUM | BINIMETINIBUM, ENCORAFENIBUM | |
| April 2026 | New protocol | L01EM03 | ALPELISIB | ALPELISIB | |
| April 2026 | New protocol | L01EN02 | PEMIGATINIBUM | PEMIGATINIBUM | |
| April 2026 | New protocol | L01EX14 | ENTRECTINIBUM | ENTRECTINIBUM | |
| April 2026 | New protocol | L01EX18 | AVAPRITINIBUM | AVAPRITINIBUM | |
| April 2026 | New protocol | L01EX19 | RIPRETINIBUM | RIPRETINIBUM | |
| April 2026 | New protocol | L01FX12 | TAFASITAMABUM | TAFASITAMABUM | |
| April 2026 | New protocol | L01FX18 | AMIVANTAMABUM | AMIVANTAMABUM | |
| April 2026 | New protocol | L01FX20 | TREMELIMUMABUM | TREMELIMUMABUM | |
| April 2026 | New protocol | L01XC-L04AJ | VASCULITE ANCA POZITIVE - DCI RITUXIMABUM**1 (original și biosimilar) și DCI AVACOPAN**1Ω | AVACOPAN, RITUXIMABUM | |
| April 2026 | New protocol | L01XK52 | COMBINAŢII (NIRAPARIBUM + ABIRATERONUM) | ABIRATERONUM, NIRAPARIBUM | |
| April 2026 | New protocol | L01XM02 | IVOSIDENIBUM | IVOSIDENIBUM | |
| April 2026 | New protocol | L04AC03 | ANAKINRA | ANAKINRA | |
| April 2026 | New protocol | L04AF-AC | ARTERITA CU CELULE GIGANTE - AGENȚI BIOLOGICI: DCI TOCILIZUMABUM**1 (concentrația 162 mg - original și biosimilar) ȘI REMISIVE SINTETICE ȚINTITE: DCI UPADACITIN… | TOCILIZUMABUM, UPADACITINIBUM | |
| April 2026 | New protocol | L04AJ01-MGG | ECULIZUMABUM | ECULIZUMABUM | |
| April 2026 | New protocol | L04AJ01-TSNMO | ECULIZUMABUM | ECULIZUMABUM | |
| April 2026 | New protocol | L04AJ03 | PEGCETACOPLANUM | PEGCETACOPLANUM | |
| April 2026 | New protocol | L04AJ07 | CROVALIMABUM | CROVALIMABUM | |
| April 2026 | New protocol | L04AL02 | ROZANOLIXIZUMABUM | ROZANOLIXIZUMABUM | |
| April 2026 | New protocol | N07XX15 | INOTERSENUM | INOTERSENUM | |
| April 2026 | New protocol | V03AE10 | NATRII ZYIRCONII CYCLOSILICAS | ||
| April 2026 | New protocol | V10XX05 | LUTETIUM (177LU) VIPIVOTIDE TETRAXETAN | LUTETIUM, VIPIVOTIDE TETRAXETAN | |
| April 2026 | Sublist changed | A16AX06 | MIGLUSTAT | C1-G29 → C1-G29/C1-G12 | |
| April 2026 | Sublist changed | B02BX08 | AVATROMBOPAG | C2-P6.27 → C2-P6.27/C1-G10 |
March 2026 · 18 changes (+11 medicines only mentioned in the text)
New protocol: 1Protocol amended: 16GP continuation changed: 1
| Month | Type | Code | Protocol | Details | Level |
|---|---|---|---|---|---|
| March 2026 | GP continuation changed | L01XE21 | REGORAFENIBUM | DA, doar medicii desemnati,conform Normelor tehnice de realizare a programelor nationale de sanatate curative → NU | |
| March 2026 | Medicine removed | L008C | IMATINIBUM | SUNITINIBUM no longer mentioned in the text | mentioned in the text |
| March 2026 | Medicine removed | R03AL09 | BECLOMETASONUM+FORMOTEROLUM+GLICOPIRONIU BROMIDUM | TRIAMCINOLONUM no longer mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01EL02 | ACALABRUTINIBUM | BENDAMUSTINUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01EL02 | ACALABRUTINIBUM | RITUXIMABUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XC28 | DURVALUMABUM | PACLITAXELUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | CISPLATINUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | DOXORUBICINUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | OXALIPLATINUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | PREDNISOLONUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | PREDNISONUM mentioned in the text | mentioned in the text |
| March 2026 | Medicine added | L01XE27 | IBRUTINIBUM | VINCRISTINUM mentioned in the text | mentioned in the text |
| March 2026 | Protocol amended | C10AX16 | INCLISIRAN | ||
| March 2026 | Protocol amended | D11AH05-A | DUPILUMABUM | ||
| March 2026 | Protocol amended | J05AX18 | LETERMOVIRUM (forma orală) | ||
| March 2026 | Protocol amended | L002G | SCLEROZA MULTIPLĂ - TRATAMENT IMUNOMODULATOR | ||
| March 2026 | Protocol amended | L008C | IMATINIBUM | ||
| March 2026 | Protocol amended | L01EE04 | SELUMETINIB | ||
| March 2026 | Protocol amended | L01EL02 | ACALABRUTINIBUM | ||
| March 2026 | Protocol amended | L01XC28 | DURVALUMABUM | ||
| March 2026 | Protocol amended | L01XE13 | AFATINIBUM | ||
| March 2026 | Protocol amended | L01XE21 | REGORAFENIBUM | ||
| March 2026 | Protocol amended | L01XE27 | IBRUTINIBUM | ||
| March 2026 | Protocol amended | L044L | PSORIAZIS CRONIC SEVER (ÎN PLĂCI) - AGENŢI BIOLOGICI ŞI TERAPII CU MOLECULE MICI CU ACŢIUNE INTRACELULARĂ | ||
| March 2026 | Protocol amended | L04AA58 | EFGARTIGIMODUM ALFA | ||
| March 2026 | Protocol amended | N03AX24 | CANNABIDIOLUM | ||
| March 2026 | Protocol amended | R03AL09 | BECLOMETASONUM+FORMOTEROLUM+GLICOPIRONIU BROMIDUM | ||
| March 2026 | Protocol amended | S01LA09 | FARICIMABUM | ||
| March 2026 | New protocol | N02CD | MIGRENA: GALCANEZUMABUM**Ω, FREMANEZUMABUM**Ω, EPTINEZUMABUM**Ω, RIM | EPTINEZUMABUM, FREMANEZUMABUM, GALCANEZUMABUM, RIMEGEPANT |
January 2026 · 42 changes (+15 medicines only mentioned in the text)
New protocol: 20Protocol amended: 13Protocol repealed: 3Medicine added: 4Sublist changed: 1GP continuation changed: 1
| Month | Type | Code | Protocol | Details | Level |
|---|---|---|---|---|---|
| January 2026 | Protocol repealed | A05AA04 | ACID OBETICHOLICUM | ||
| January 2026 | Protocol repealed | L04AX08 | DARVADSTROCEL | ||
| January 2026 | Protocol repealed | S01EE05 | TAFLUPROSTUM | ||
| January 2026 | GP continuation changed | L01XE21 | REGORAFENIBUM | NU → DA, doar medicii desemnati,conform Normelor tehnice de realizare a programelor nationale de sanatate curative | |
| January 2026 | Medicine removed | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | TUBERCULINUM no longer mentioned in the text | mentioned in the text |
| January 2026 | Medicine removed | L041M | SPONDILOARTRITA AXIALĂ, INCLUZÂND SPONDILITA ANCHILOZANTĂ ȘI SPONDILOARTRITA AXIALĂ NONRADIOGRAFICĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR)… | TUBERCULINUM no longer mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | ABROCITINIBUM | of the protocol |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | APALUTAMIDUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | EFAVIRENZUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | ENZALUTAMIDUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | FLUCONAZOLUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | FLUOXETINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | FLUVOXAMINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | RIFAMPICINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | TICLOPIDINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | UPADACITINIBUM | of the protocol |
| January 2026 | Medicine added | L01XC28 | DURVALUMABUM | GEMCITABINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | L01XE10A | EVEROLIMUS | EXEMESTANUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | CICLOSPORINUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | FILGOTINIBUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | TACROLIMUSUM mentioned in the text | mentioned in the text |
| January 2026 | Medicine added | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | RISANKIZUMABUM | of the protocol |
| January 2026 | Medicine added | L041M | SPONDILOARTRITA AXIALĂ, INCLUZÂND SPONDILITA ANCHILOZANTĂ ȘI SPONDILOARTRITA AXIALĂ NONRADIOGRAFICĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR)… | TOFACITINIBUM | of the protocol |
| January 2026 | Protocol amended | B01AC24 | TICAGRELOR | ||
| January 2026 | Protocol amended | B01AE-B01AF | ANTICOAGULANTE ORALE NON-ANTI VITAMINA K (NOAC) | ||
| January 2026 | Protocol amended | D11AH-L04AA | DERMATITA ATOPICĂ - AGENŢI BIOLOGICI: DUPILUMABUM**1Ω ȘI INHIBITORI DE JAK: BARICITINIBUM**1Ω, UPADACITINIBUM (15 mg, 30 mg)**1Ω, ABROCITINIBUM**1Ω | ||
| January 2026 | Protocol amended | L01XC28 | DURVALUMABUM | ||
| January 2026 | Protocol amended | L01XE10A | EVEROLIMUS | ||
| January 2026 | Protocol amended | L01XE21 | REGORAFENIBUM | ||
| January 2026 | Protocol amended | L034K | BOALĂ CRONICĂ INFLAMATORIE INTESTINALĂ | ||
| January 2026 | Protocol amended | L040M | ARTRITA PSORIAZICĂ – AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR), CERTOLIZUMABUM**1, ETANERCEPTUM**1 (ORIGINAL ŞI BIOSIMILAR), GOLIMUMABUM**1, IN… | ||
| January 2026 | Protocol amended | L041M | SPONDILOARTRITA AXIALĂ, INCLUZÂND SPONDILITA ANCHILOZANTĂ ȘI SPONDILOARTRITA AXIALĂ NONRADIOGRAFICĂ - AGENŢI BIOLOGICI: ADALIMUMABUM**1 (ORIGINAL ŞI BIOSIMILAR)… | ||
| January 2026 | Protocol amended | M05BX04 | DENOSUMAB (60 mg/ml) | ||
| January 2026 | Protocol amended | M09AX10 | RISDIPLAMUM | ||
| January 2026 | Protocol amended | R03DX05-UCS | URTICARIE CRONICĂ SPONTANĂ – TERAPIE BIOLOGICĂ | ||
| January 2026 | Protocol amended | S01LA05 | AFLIBERCEPTUM | ||
| January 2026 | New protocol | B02BX08 | AVATROMBOPAG | AVATROMBOPAG | |
| January 2026 | New protocol | B06AC06 | BEROTRALSTATUM | BEROTRALSTATUM | |
| January 2026 | New protocol | C10AX16 | INCLISIRAN | INCLISIRAN | |
| January 2026 | New protocol | D11AH05-BPOC | DUPILUMABUM | DUPILUMABUM | |
| January 2026 | New protocol | D11AH05-PN | DUPILUMABUM | DUPILUMABUM | |
| January 2026 | New protocol | L01EL03 | ZANUBRUTINIBUM | ZANUBRUTINIBUM | |
| January 2026 | New protocol | L01EX22 | SELPERCATINIBUM | SELPERCATINIBUM | |
| January 2026 | New protocol | L01XC38 | ISATUXIMABUM | ISATUXIMABUM | |
| January 2026 | New protocol | L01XX60 | TALAZOPARIBUM | TALAZOPARIBUM | |
| January 2026 | New protocol | L01XX75 | TEBENTAFUSPUM | TEBENTAFUSPUM | |
| January 2026 | New protocol | L02BB06 | DAROLUTAMIDUM | DAROLUTAMIDUM | |
| January 2026 | New protocol | L02BX04 | RELUGOLIXUM | RELUGOLIXUM | |
| January 2026 | New protocol | L04AA58 | EFGARTIGIMODUM ALFA | EFGARTIGIMODUM ALFA | |
| January 2026 | New protocol | M05BX04-ONCO | DENOSUMAB | DENOSUMABUM | |
| January 2026 | New protocol | M05BX07 | VOSORITIDUM | VOSORITIDUM | |
| January 2026 | New protocol | N03AX24 | CANNABIDIOLUM | CANNABIDIOLUM | |
| January 2026 | New protocol | N03AX26 | FENFLURAMINUM | FENFLURAMINUM | |
| January 2026 | New protocol | N07XX18 | VUTRISIRANUM | VUTRISIRANUM | |
| January 2026 | New protocol | R03DX11 | TEZEPELUMABUM | TEZEPELUMABUM | |
| January 2026 | New protocol | S01LA09 | FARICIMABUM | FARICIMABUM | |
| January 2026 | Sublist changed | M05BX04 | DENOSUMAB (60 mg/ml) | C2-P3 → C1-G22 |